The Powerpuff Girls face their greatest challenge in this 10th anniversary special episode. There exists a Key to the World, which is handed from city to city on an annual basis. Whoever possesses the key rules over the entire world. When the key is delivered to Townsville, every villain in Townsville attempts to retrieve it. When the girls procure it for themselves, they quickly get sucked into a power struggle, fighting the villains and themselves over who gets to rule the world.

The Amoeba Boys want to be "bad guys" but they so don't know how. So they ask the Powerpuff Girls to show them.

The Powerfuff Girls kick butt but dispel all doubts: Mojo Jojo's the star of The Mane Event's great bonus features. In "Mojo Jojo's Evil Bio," Mojo narrates his life story -- and even does an audio commentary! Also includes two never-before-seen episodes. And when Bubbles and Buttercup accidentally cut Blossom's hair too short, she makes them take on the Eyeball-Monster by themselves.

When Princess Morebucks finds out that she's been put on Santa's naughty list (in fact, she's the only one on it!), she does a quick re-write, resulting with Bubbles, Blossom, and Buttercup with nothing but coal for Christmas! On top of all that, Princess gets the one thing she wants for the holidays: super powers! Now, the girls have to stop Princess and make sure that Christmas is saved for children everywhere.

In honor of the 10th anniversary of the "Powerpuff Girls" series, the cast and crew reminisce about the cartoon's development and history.

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‘The Lions Rule’ is the saga of three lion families linked together by a strange, charmed place called the Glade: a beautiful oasis in Ruaha National Park where there is always water. The Glade is the territory of two old lionesses and their cubs. The Glade pride can bring down an adult giraffe – a remarkable skill. A magical Baobab forest spreads out beyond the Glade. This is the territory of the Baobab pride. They are the largest pride in all of Ruaha. The third pride are drifters – lean, mean and ruthless. They are the Njaa. The Njaa follow the buffalo. The herd is their territory and they are experts in the dark art of the buffalo kill. All three prides are lead by lionesses; there are no adult males in residence. This will play a major role in their fates

Kids send in videos to Rule The Mix and a boy and girl pick them and play them on, Rule The Mix.

Without the Tuck Rule, Tom Brady wouldn't have won his first playoff game – and who knows where his destiny might have gone from there. But whether what happened on January 19, 2002 was the right call or a terrible call, divine providence or deep conspiracy, one thing is certain: The life of Tom Brady, as well as the life of the Hall of Famer who hit him on the play, Brady's college teammate Charles Woodson, was forever changed that night.

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